ELOVL6 and asthma: The expression of ELOVL6 is enhanced in the bronchial epithelial cells of patients with severe asthma, and both Th2 and non-Th2 inflammation is enhanced with increases in ceramides and S1P in ELOVL6-deficiency mice, suggesting that ELOVL6 may be a novel target molecule for the treatment of asthma [185,186].