Moreover, multiple linear regression analysis has demonstrated that the presence of Hashimoto thyroiditis is significantly associated with serum catestatin levels, independent of age, BMI, systolic blood pressure, AGEs, hsCRP, TSH and anti-TPO serum concentrations (β 1.819, SE 0.830, p = 0.030) (Supplementary Tables S1 and S2). Here, TPO is linked to Hashimoto thyroiditis.