ALKBH5 was highly expressed in various cancers, including non-small-cell lung cancer [53,54,55], glioblastoma (GBM) [38], hepatocellular carcinoma [56], colorectal cancer [57], gastric cancer [58], endometrial cancer [59], and breast cancer [60], with high expression of ALKBH5 being closely related to the malignancy of these tumors. The gene discussed is ALKBH5; the disease is colorectal cancer.