CRP and bacterial infectious disease: The study published by Milcent et al. in 2016 showed that PCT provides higher accuracy in identifying invasive bacterial infection (IBI) in neonates and infants less than 90 days of age compared to that of CRP; indeed, the AUC ROC curve for the detection of IBI for PCT was higher than that for CRP concentration (AUC, 0.91; 95% CI 0.83–0.99; vs. AUC, 0.77; 95% CI, 0.65–0.89; p = 0.002) [70].