Remarkedly, the FGF/FGFR1/NOTCH1 within RB1 variant group has a dramatically higher inner‐tumor CD8+ T cell infiltration (Figure 5E,F), following more CD8+PD‐1‐LAG3‐ non‐exhausted T cells (Figure 5E,G) and CD8+PD‐1+LAG3‐ exhausted T cells (Figure 5E,H). The gene discussed is RB1; the disease is neoplasm.