Our previous investigations indicated that Ras homolog family member A (RhoA) is upregulated in endometriosis and is intricately linked to the E2/ERα/ERK signaling pathway, thereby promoting epithelial‒mesenchymal transition (EMT) and proliferation, ultimately contributing to endometriosis development (Huang et al. 2020). This evidence concerns the gene RHOA and endometriosis.