NF1 and neurofibromatosis type 1: We performed a postmortem study of three children aged <10 years old with high-grade midline gliomas—two (PD50297 and PD51123) with sporadic tumors (H3F3A K27M mutant) and one with neurofibromatosis type 1 with a pathogenic truncating NF1 (c.3113 + 1G>A) germline mutation.