TERT and lung carcinoma: Based on our observations we concluded that lung cancer cells and telomerase positive iPSC (CHiPSC22) express a novel TERT isoform called Delta 2–4 that retains the original open reading frame and potentially codes for a new protein and that HBECs that lack telomerase activity do not express Delta 2–4 isoform making the Delta 2–4 isoform restricted to cells that express appreciable levels of TERT.