IFNG and myeloid sarcoma: CCR2 has also been reported to contribute to EAE by mediating recruitment to the central nervous system of a GM-CSF-producing subgroup of cells characterized as CCR6−CCR2+53; and CCR2+CCR5+ Th cells that could produce IFN-γ in response to myelin basic protein were found to be enriched in the CSF of patients with MS during relapse35.