TBC1D2 and cervical cancer: Additionally, TBC1D2ACC, but not TBC1D2APH or TBC1D2AGAP, colocalized with RAB33A, while only TBC1D2A∆CC did not colocalize with RAB33A (Fig. 5h, i); these results strongly suggested that RAB33A recruited TBC1D2A through its CC structural domain to inactivate RAB7 in cervical cancer cells.