In fact, the morphology of RAB33A-overexpressing cervical cancer cells was altered, and RAB33A increased the formation of both linear and lamellar pseudopods according to phalloidin staining results (Supplementary Fig. S2a); these results indicated that Rho family members, which are involved in cytoskeletal modulation, may participate in the promotion of migration and invasion by RAB33A in cervical cancer cells. Here, RAB33A is linked to cervical carcinoma.