To evaluate the prognostic value of PD-L1 expressed on tumor VECs (tumor-VECs-PD-L1, TEC-PD-L1) in NPC patients, we analyzed the relationship between TEC-PD-L1 in 180 NPC tissue sections from Sun Yat-sen University Cancer Center and patients’ OS and PFS. This evidence concerns the gene CD274 and nasopharyngeal carcinoma.