HUVECs were pretreated with NF-κB signaling pathway inhibitors R7050 (10 μM) [15] and BAY 11-7082 (10 μM) [16], as well as the STAT3 inhibitor Stattic (10 μM) [17], for 1 h before the addition of NPC tumor cell supernatants. This evidence concerns the gene STAT3 and nasopharyngeal carcinoma.