Because our data indicated that Trem2 exerted a strong renal protective effect on the AKI–CKD transition, it was of interest to determine whether adoptive cell therapy using an immortalised BMDM cell line overexpressing TREM2 (TREM2OE‐iMφ) could reduce the AKI–CKD transition. The gene discussed is TREM2; the disease is acute kidney injury.