In HCC cases, TM4SF4 was expressed in all seven cases whereby membranous TM4SF4 expression in HCC cells on all sides of the plasma membrane domains were present in 85.7% (n = 6/7) of the HCC cases, in accordance with HPA’s interpretation of “Distinct membranous immunoreactivity was observed in liver and pancreatic cancers”. The gene discussed is TM4SF4; the disease is familial pancreatic carcinoma.