USP47 and gastric cancer: To investigate the biological impact of USP47 on GC, we established stable USP47-knockdown cell lines using 2 independent shRNAs in HGC-27, GT38, SNU719, and SNU668 cell lines, as well as USP47-overexpressing cell lines by transfecting USP47 expression plasmids into HGC-27 and GT38 cells.