GPR65 and neoplasm: GPR65 KO or m.CR tumors [red fluorescent protein–positive (RFP+)] and host immune cells (CD45.2+ Thy1.1− RFP−) were isolated from the spleen of tumor-bearing mice prior to CAR T-cell treatment (day 7) and 4 days after treatment (day 11) and analyzed (Supplementary Fig. S5A).