These variables included age, two-stage overlap (fever and hypotensive stage overlap or hypotensive and oliguria stage overlap), three-stage overlap (fever, hypotensive, and oliguria stage overlap), qSOFA ≥ 2, RBC or HGB elevation, thrombocytopenia, WBC or neutrophil elevation, ALT or AST elevation, direct bilirubin elevation, creatinine or uric acid elevation, and hypochloremia. The gene discussed is GPT; the disease is Thrombocytopenia.