MUC3A and myotonic dystrophy type 2: SS3/4 and other bacteria such as Akkermansia mucinphila (which stimulates mucus production by the intestinal mucosa through degeneration of intestinal mucin) was reduced, as shown in a 2012 study by Qin et al., in which they studied the microbiota of DM2 patients (specifically, 345 individuals) using an MGWAS (metagenome-wide association study) [181].