In addition, ginsenoside Rg1 significantly alleviated neuronal injury by reducing the levels of IL-6, IL-1β, and ROS and inhibiting the AIM2 inflammasome in rat brains, while ginsenoside Rg5 was able to reduce the levels of inflammatory cytokines TNF-α and IL-1β and improve cognitive deficits in a dose-dependent manner [8,9]. The gene discussed is IL1B; the disease is Cognitive impairment.