STUB1 and stroke disorder: In a fixed-effects meta-analysis [5], it was found that individuals with any CHIP mutation had a 14% increased risk of total stroke (95% CI, 1.03–1.27; p = 0.01), particularly driven by a 24% increase in the odds of hemorrhagic stroke (HS) (95% CI, 1.01–1.51]; p = 0.04), such as subarachnoid hemorrhage (SAH) [5].