The highest level of significance was observed for the RAD23 homologous B gene (eg14919562), the PEX14 gene (peroxisomal biogenesis factor 14) (eg14170597), the TN-X gene (tenascin XB) (cg03822479), etc. A decrease in methylation levels in the RAD23 gene was seen in women with osteoporosis, while methylation levels were increased in four women [10]. The gene discussed is TNXB; the disease is osteoporosis.