The main findings of this study were: (1) PIV is an independent predictor of 1-year MACEs in non-ST-segment elevation ACS patients; (2) PIV is a potential marker for predicting MACEs, regardless of MI or C-reactive protein levels; and (3) PIV appears superior to other blood cell-derived indices in predicting MACEs in patients with unstable angina and non-ST-segment elevation MI. The gene discussed is CRP; the disease is angina pectoris.