ITGA2B and peripheral vascular disease: In terms of the secondary endpoints, multivariate Cox regression analysis identified (a) frailty as the only independent poor prognostic indicator of all-cause mortality, (b) DES implantation and peripheral vascular disease as the only independent poor prognostic indicators of cardiovascular mortality, and (c) the use of GP IIb/IIIa inhibitor as the only independent good prognostic indicator for ACS or TLR (Table 4).