The genetic drivers of PH have been investigated, where one study investigated the molecular connections between COVID-19 and PAH by integrating protein–protein interactions and transcriptomic data from patients and identified shared molecular mechanisms and transcriptional regulators common to both diseases, including RUNX1, HIF1A, JUN, STAT1, STAT3, and NFKB1 [41]. Here, HIF1A is linked to COVID-19.