The mean values of glucose, insulin, HOMA-IR, TG, hs-CRP, LH, total testosterone, FAI, and DHEA-S were noted to be higher among subjects in the PCOS group (all, p <0.05); however, the mean levels for HDL-C and SHBG of PCOS patients were significantly lower when compared with healthy subjects (all, p < 0.05). The gene discussed is SHBG; the disease is polycystic ovary syndrome.