A further 24 (25%, 19 BRF and 5 BRM) had documented issues which were considered likely (but not specialist-confirmed) to be medication-related including worsened mental health; elevated blood parameters of testosterone, oestrogen, prolactin, HCT, Hb or cholesterol; uro-gynaecological problems and acne. This evidence concerns the gene GSTM1 and acne.