IDH3A and neoplasm: According to the literature [21], it is possible to identify negative prognostic factors, including putaminal [34] or paralimbic involvement and tumor grading, and positive prognostic factors, including clinical onset with comitial seizures, isocitrate dehydrogenase (IDH) mutation, greater extent of resection [14], age [35], female sex, and Karnofsky performance status [36].