The predominant AEs were elevated AST (12/25, 48%), elevated ALT (10/25, 40%), abdominal pain or bloating (10/25, 40%), vomiting (9/25, 36%), dysuria (7/25, 28%), hand-foot syndrome (7/25, 28%), hypoproteinemia (7/25, 28%), elevated blood pressure (7/25, 28%), and leukopenia (5/25, 20%) in the HLP group. The gene discussed is GPT; the disease is Decreased total leukocyte count.