Likewise, a study on an animal model showed that IL-17F induced expression of neutrophil-attracting chemokines CXCL1 and CXCL5 in kidney cells, leading to the development of renal tissue injury, which could be important for the development of anti-IL-17 cytokine therapies in TH17-mediated human autoimmune diseases [26]. Here, CXCL5 is linked to autoimmune disease.