The qPCR experiment showed that the transcription levels of IL-1β, IL-6, and TNF-α in the circ-ZNF277 suppressed THP-1 cells were lower than those in the control THP-1 cells at 0, 12, and 24 h post-infection (p < 0.001) (Figure 6A,E,I). This evidence concerns the gene IL1B and infection.