The overall objective of this research was to evaluate the anticonvulsant and antiepileptogenic properties of an aqueous extract of Mimosa pudica in the pilocarpine–picrotoxin model of temporal lobe epilepsy and investigate the effects of the aqueous extract of Mimosa pudica leaves and stems on some parameters of status epilepticus and epileptic convulsions, oxidative and nitrosative stresses, GABAergic and cholinergic transmissions, and the expression of BDNF. The gene discussed is BDNF; the disease is status epilepticus.