92 adults with T2DM, aged 20–65 years, not receiving insulin, recruited from Iran Diabetes Society and the general population, with BMI 28.4 ± 0.79 for Group 1, 29.7 ± 0.72 for Group 2, and 29.2 ± 0.68 for Group 3. The gene discussed is INS; the disease is type 2 diabetes mellitus.