ENTPD8 and cancer: Furthermore, we utilized the Tumor Immune Single-cell Hub 2 (TISCH) database to further analyze the relationship between ENTPD8 and the mortality risk of different cancer types, and the results indicate a trend of negative correlation between ENTPD8 expression and the mortality risk in patients with HCC, but it was worth noting that there was no statistical significance between the two (Figure 1C).