In the mouse model of liver fibrosis induced by thioacetamide, ginsenoside was shown to inhibit the entry of IL-1β and IL-18 into the extracellular matrix by regulating ERRα-P2X7r signaling pathway, thereby reducing inflammatory responses, improving hepatocyte damage, and suppressing liver fibrosis (70). The gene discussed is IL18; the disease is Hepatic fibrosis.