Results showed that the CSF GAP-43 × AT(N) group interaction was associated with episodic memory performance, such that greater levels of CSF GAP-43 were associated with worse episodic memory performance in the Alzheimer’s disease continuum group relative to the no Alzheimer’s disease pathology group (Table 4; Fig. 2A). This evidence concerns the gene GAP43 and early-onset autosomal dominant Alzheimer disease.