Yoon et al. (2020) generated CRISPR/Cas9-derived mutations in the eukaryotic translation initiation factor 4E (eIF4E) in the tomato cultivar Micro-Tom, and evaluated the role of eIF4E in Potyvirus resistance. Results demonstrated that eIF4E was a susceptible factor which is necessary for pepper mottle virus (PepMoV) infection (Yoon et al., 2020). Here, EIF4E is linked to infection.