In addition, among individuals with APA/APN and APMs <20, heart mass and LV wall thickness were the highest, and the number of CV pathologies (i.e., moderate or severe CAD, aortic atherosclerosis, cerebrovascular occlusion, and heart fibrosis) was the greatest when compared with individuals with diffuse CYP11B2 positivity or APMs ≥20. The gene discussed is CYP11B2; the disease is aortic atherosclerosis.