Research results indicated that Sch B significantly inhibited the lung and bone metastasis of 4T1 mouse breast cancer cells by inhibiting TGF-β-induced epithelial-mesenchymal transition (EMT), suggesting the targeted effect of Sch B on breast cancer metastasis (Liu et al., 2012; Zhang et al., 2013). This evidence concerns the gene TGFB1 and breast cancer.