Research results indicated that Sch B significantly inhibited the lung and bone metastasis of 4T1 mouse breast cancer cells by inhibiting TGF-β-induced epithelial-mesenchymal transition (EMT), suggesting the targeted effect of Sch B on breast cancer metastasis (Liu et al., 2012; Zhang et al., 2013). The gene discussed is TGFB1; the disease is breast carcinoma.