EIF2A and brain injury: The neuroprotective effects of salubrinal in a murine model of mild traumatic brain injury (mTBI) have been demonstrated by Rubovitch et al. to be achieved by maintaining the levels of p-eIF2a, but not the total ATF4, after mTBI, that is evidenced by the significant reduction in p-eIF2α protein levels observed in the post-mTBI ipsilateral cortex [137].