There are 4 (PTK6, CDK1, AURKA and EPHB2) and 10 kinases (PAK1, PKMYT1, AURKB, CHEK1, CDK1, JAK3, EPHB2, PRKCG, PTK6 and AURKA) of the Hannover‐AD and TCGA cohort whose gene expression and kinase activities were upregulated in the same way. The gene discussed is CHEK1; the disease is Alzheimer disease.