TP53 and neoplasm: In the same way, we analysed SQ tumours (LUSC), and for upregulated DEGs (range 6–194‐fold), the hallmark gene sets were similar to AD cases, that is, mitotic spindle, E2F targets, G2M checkpoints and mTOR signalling, while KEGG pathway analysis highlighted p53 signalling, cell cycle and cellular senescence.