PRPH and amyotrophic lateral sclerosis: The discovery of peripherin in ubiquitinated inclusions and the identification of genetic variants of the peripherin gene, particularly the insertion PRPH (IVS8)(−36insA), deletion PRPH (228delC), and missense variations c.421G > T (p.D141Y) and c.398 G > C (p.R133P) in ALS patients, which disrupt the assembly of the neurofilament network in transfected cells, further supporting its role in pathogenesis of this neurodegenerative disorder (Corrado et al. 2011; Gros‐Louis et al. 2004; Leung et al. 2004) (Table 3).