Diabetes mellitus, a chronic disease in which a patient has a metabolic disorder in the endocrine system with abnormally high blood glucose levels, is responsible for one death in every fifth second in 2021.[1] It is one of the major noncommunicable and growing diseases throughout the world, increased by 3% over the last 20 years, and estimated that more than 650 million adults develop diabetes by the year 2045.[2] Diabetic patients have problems producing (Type 1) or efficiently using (Type 2) insulin hormone in the body. This evidence concerns the gene INS and diabetes mellitus.