Furthermore, as shown in Fig. 6B and Additional file 1: Fig. S5B-8B, SMARCAL1 demonstrated positive associations with the infiltration levels of Type 2 T helper cells (R = 0.28) and Activated CD4 T cells (R = 0.26) in Glioma (Fig. 6C), Type 2 T helper cells (R = 0.24) in LIHC (Additional file 1: Fig. S6C), Memory B cells (R = 0.33) and Regulatory T cells (R = 0.29) in KIRC (Additional file 1: Fig. S7C), as well as Type 2 T helper cells (R = 0.29) in UCEC (Additional file 1: Fig. S8C). Here, CD4 is linked to central nervous system cancer.