In patients with breast cancer, the specific altered BRCA gene is known to be associated with different clinicopathologic features, with the majority of tumors being triple-negative in BRCA1 carriers and hormone receptor–positive/HER2-negative in BRCA2 carriers.7,8,24,25 These peculiar biologic features were also observed in our study. This evidence concerns the gene BRCA1 and breast carcinoma.