PTPRC and Menorrhagia: Notably, CD45 on granulocyte (IVW: odds ratio [OR] = 0.916, 95% CI: 0.880–0.954, P = 1.974 × 10−5; MR Egger: OR = 0.942, 95% CI: 0.835–1.064, P = .361; weighted median: OR = 0.959, 95% CI: 0.906–1.016, P = .160) was associated with a potential decreased risk of menorrhagia.