Of note, the modulated HERVs not only belongs to the groups already investigated for CRC, namely HERV‐H and HML2, but also to additional 24 clades not previously investigated in this context and observed to be modulated in the present study for the first time, particularly HERV‐E, HERV‐9, and HERV‐IP. The gene discussed is CLEC10A; the disease is colorectal carcinoma.