The high expression of autophagy-related proteins, such as p62, WDFY3, and NQO1, in acinar cells near pancreatic steatosis, especially in acinar-ductal metaplasia and pancreatic cancer cells, indicates a link between autophagy disruption, oxidative stress, DNA damage, and pancreatic cancer (112). Here, NQO1 is linked to familial pancreatic carcinoma.