YEATS2 also can act as a target of HIF1α and regulate the TAK1/NF‐κB pathway to promote tumor progression in pancreatic cancer, highlighting its potential as a therapeutic target in various cancer types including lung cancer (YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration).These findings underscore the significance of YEATS2 in the molecular pathology of lung cancer, suggesting its potential as a target for therapeutic intervention in cancer treatment. Here, YEATS2 is linked to familial pancreatic carcinoma.