MARK2 and neoplasm: These key genes were found to be involved in “Cell Cycle,” “Cellular senescence,” “Oocyte meiosis,” “Regulation of cyclin-dependent protein serine/threonine,” “kinase activity,” and “protein serine/threonine kinase activator activity.” According to KEGG pathway analysis, CDK1 and its related genes are closely related to “Progesterone-mediated oocyte maturation.” Protein kinase I (PGG-I) is dependent on cyclic guanosine phosphate (cGMP) and is a member of the serine/threonine kinase family that is important for tumor development.