We observed that MATN3 expression at the promoter methylation level was higher in tumor tissues of KIRP (Figure 6F), LUAD (Figure 6D), and LUSC (Figure 6B) than in normal tissues of these cancer types, and was opposite in BLCA (Figure 6I), LIHC (Figure 6H), PCPG (Figure 6C), STAD (Figure 6J), TGCT (Figure 6E), and UCEC (Figure 6G). The gene discussed is MATN3; the disease is neoplasm.