The results showed that MATN3 expression was positively correlated with cytotoxic T lymphocyte antigen 4 (CTLA4), CD274 (PD-L1), programmed cell death 1 (PDCD1 or PD1), and lymphocyte activation gene 3 (LAG3) in the majority of cancer types, but the opposite was true for THYM, which was negatively correlated with most of the immune checkpoint genes (Figure 4A). Here, CD274 is linked to cancer.