LINC03124 and gastric cancer: Additionally, we observed that the suppression of C2orf27A effectively repressed NOX4 expression at both the transcriptional and translational levels, with functional rescue experiments revealing that the concurrent upregulation of NOX4 upon C2orf27A knockdown could partially reverse the C2orf27A-induced anti-proliferative and pro-apoptotic effects on GC cells.